Slimi 60mg Pot 21pcs

Uses of Slimi 60

• Treats obesity (weight loss) along with a reduced calorie and lower-fat diet

How does Slimi 60 work?

Slimi 60 Capsule helps in reducing body weight by blocking the action of enzymes in your gut that digest fat in the diet. This prevents the fat from being absorbed into the body and allows the undigested fat to pass out of the body via the feces.

Side Effects of Slimi 60

• Headache
• Vomiting
• Unusual Tiredness And Weakness
• Tooth Problems
• Trouble Sleeping
• Itching
• Yellow Colored Eyes Or Skin
• Abdominal Pain
• Abnormal Bowel Movements
• Menstrual Changes
• Rectal Pain

Quick Suggestions:

• Slimi 60 is used to aid weight loss in obese individuals.
• It should be used along with regular physical activity and a healthy diet.
• Take it during or up to 1 hour after each meal.
• Skip your dose if you miss a meal or if your meal contains no fat.
• A multivitamin supplement containing vitamins A, D, and K is recommended when taking Slimi 60.
• It should not be taken for longer than six months. If you have been unable to lose weight after 12 weeks of taking this medicine, you should stop taking it and consult your doctor.

Indication

Slimi 60 Capsule is a medicine used to treat obesity, which is a medical problem involving an excessive amount of body fat. Being obese may increase your risk of developing other health problems, including diabetes and high blood pressure. 

Pharmacology

Orlistat is a potent, selective, and long-acting lipase inhibitor. Its mechanism of action involves forming a covalent bond with the active serine site of gastric and pancreatic lipases found in the stomach and upper small intestine. This interaction inactivates the enzymes, preventing the conversion of dietary fats (triglycerides) into absorbable free fatty acids and monoglycerides. Consequently, undigested triglycerides cannot be absorbed, leading to a calorie deficit and promoting weight loss. Notably, orlistat's activity is localized to the gastrointestinal tract, and it does not require systemic absorption for its effects. The recommended therapeutic dose of orlistat is 120 mg taken three times a day to inhibit the absorption of dietary fats.

Dosage & Administration of Slimi 60

Slimi 60 Capsule should be taken with food, either immediately before, during or up to 1 hour after each main meal. If a meal is missed or contains no fat, the dose can be omitted. It is essential to follow the advice of your physician regarding the dosage and duration of the medication, considering factors such as your age, body weight, and medical condition. Swallow the capsule with a glass of water without crushing or chewing it.

For adults:

• If the pretreatment Body Mass Index (BMI) is greater than 30 kg/m², or BMI is greater than 27 kg/m² with other risk factors or diseases (e.g., hypertension, diabetes, hyperlipidemia), the recommended dose is 120 mg three times daily with each main meal.
• For patients with a BMI greater than 28 kg/m² regardless of other risk factors, the recommended dose is 60 mg three times daily.
• If a meal is missed or contains no fat, the dose should be skipped.
• Discontinue the medication if the patient is unable to lose at least 5% of their body weight during the first 12 weeks of therapy.

For children:

• The safety and efficacy of Slimi 60 have not been established for children under 12 years of age.

Always consult your healthcare provider before starting or stopping any medication, and do not discontinue Slimi 60 Capsule without your doctor's advice.

Interaction

Taking more than one medicine or combining medications with certain foods or beverages can lead to potential drug interactions, which may affect the effectiveness of the drugs or cause unwanted side effects. Here are some important interactions related to Slimi 60 Capsule:

Interaction with Alcohol: The interaction between Slimi 60 Capsule and alcohol is unknown. To ensure safety, it is advisable to consult your doctor before consuming alcohol while on this medication.

Interaction with Lab Tests: There is no specific information available regarding interactions with lab tests.

Interaction with Other Medicines:

• Warfarin: Slimi 60 Capsule may increase the risk of bleeding by affecting the absorption of vitamin K. Any symptoms of dizziness, blood in stools, or unusual bleeding should be reported to the doctor. Monitoring of prothrombin time is necessary, and dose adjustments may be required based on the clinical condition.
• Antidiabetic medicines: Changes in body weight due to Slimi 60 Capsule may alter blood glucose levels. Symptoms of dizziness, confusion, weakness, or palpitations should be reported to the doctor, and the dose of antidiabetic medicines may need to be reduced based on blood glucose levels.
• Cyclosporine: Slimi 60 Capsule may reduce the effect of cyclosporine by decreasing its absorption. Inform your doctor if you are taking either of these medications. If coadministration is needed, cyclosporine should be taken 2 hours before or after Slimi 60 Capsule. Monitoring of the patient's clinical condition is necessary.

1. Interaction with Disease:

• Malabsorption: Slimi 60 Capsule may worsen the condition in patients with malabsorption due to decreased absorption of vitamins, minerals, and fats. Therefore, it is not recommended in patients with digestive system disorders and cholestasis.
• Diabetes: Slimi 60 Capsule should be used with caution in patients with diabetes due to an increased risk of low blood glucose levels. The dose of antidiabetic medicines should be reduced based on the clinical condition.

1. Interaction with Food: There is no specific information available regarding interactions with food.

It's crucial to inform your healthcare provider about all the medications you are taking, including over-the-counter drugs, supplements, and herbal products, to avoid potential drug interactions and ensure safe and effective treatment. Always follow your doctor's advice and report any unusual symptoms or concerns during your medication regimen.

Contraindications

• If you are allergic to orlistat or any other component of Slimi 60
• If you have severe malabsorption disorder, a condition in which your body isn’t able to take in many of the nutrients from the food you eat.
• If you have or had a liver disease.
• If you are a breastfeeding mother.

Pregnancy & Lactation

Pregnancy and lactation: No clinical data on Orlistat use during pregnancy is available. Orlistat does not appear to be excreted in breast milk. Orlistat should not be taken when nursing.

Precautions & Warnings

Before administering Orlistat, it is essential to rule out organic causes of obesity, such as hypothyroidism. Orlistat should not be taken at the same time as cyclosporine. For patients taking both medications, cyclosporine should be administered at least 2 hours before or after Orlistat. Regular monitoring of cyclosporine levels is necessary.

In a clinical investigation, the reduction in body weight with Orlistat was found to be less in individuals with type II diabetes compared to non-diabetic participants. During Orlistat therapy, anti-diabetic medication should be carefully managed, and the dose of oral antidiabetics or insulin may need to be adjusted based on improvements in glycemic control.

Patients using Orlistat should be encouraged to follow dietary guidelines. Taking Orlistat with a fatty meal may increase the likelihood of gastrointestinal side effects. Therefore, fat intake should be spread out among three large meals each day. Orlistat has been reported to interfere with the absorption of several fat-soluble vitamins and beta-carotene. Hence, patients should be strongly encouraged to take a multivitamin supplement containing fat-soluble vitamins to ensure proper nutrition. Additionally, obese patients may have low levels of vitamin D and beta-carotene compared to non-obese patients.

Storage Conditions

Store in a cool & dry place below 30°C, protect from light & moisture. Keep out of reach of children.